Many non integrating reprogramming strategies have been inve

2018-10-20

Many non-integrating reprogramming strategies have been investigated over the past 8 years, such as minicircle plasmids, synthetic mRNA/miRNA, proteins, and small molecules. However, all these approaches are labor intensive, time consuming, and often inefficient. Recently, much attention has been fo

While this manuscript was in preparation Gutschner

2018-10-20

While this manuscript was in preparation, Gutschner et al. (2016) also described a version of SpCas9 fused to the N-terminal region of human Geminin. Although the authors reported a modest increase (28%–87%) in HR compared with unmodified SpCas9 in HEK293T cells, their Cas9-Geminin fusion provoked s

DENV as one of the most widespread vector borne viruses

2018-10-20

DENV, as one of the most widespread vector-borne viruses, infects millions of people each year worldwide. However, no clinically approved drugs are yet available against DENV. There is an urgent need to develop effective anti-DENV drugs for such treatment. In this study we tested IFN-α2a, chloroquin

Hello world!

2018-07-29