• br Tests and measurements We

  2020-05-06

  

  Tests and measurements We used a set of FPGA cores for all tests and measurements. Firstly, the control circuit for the Controlled Current Limiter illustrates the proposed TMR method. The circuit contains a D-Register to enable or disable the power to the protected device, a counter, which is use

• The present study was the

  2020-05-06

  

  The present study was the first to examine how COMT genotype and estradiol are associated with DBU receptor functioning in healthy postmenopausal women. We hypothesized that with decreased circulating estradiol after menopause, the COMT genotype relationship to cognition would remain and perhaps be

• br Acknowledgments br Introduction Understanding the charact

  2020-05-06

  

  Acknowledgments Introduction Understanding the characteristics of the Amazonian Dark soils “Terras Pretas de Índio” (TPIs) is of ecological importance, because the TPI soils represent a residue-based model for tropical sustainable agriculture (Sombroek et al., 2003, Neves et al., 2003, Cohen-O

• In contrast to drospirenone dydrogestrone

  2020-05-06

  

  In Azithromycin Dihydrate to drospirenone dydrogestrone acts rather neutral at the aldosterone-, glucocorticoid- and androgen-receptor [12]. This indicates that the assessment of a ‘net-overall effect’ on the vascular system is very difficult based on the often discussed ‘partial effects’ of the pr

• The ADME profile of AAT

  2020-05-06

  

  The ADME profile of AAT-008 () was very promising, with high stability in HLM. The pre-clinical pharmacokinetic properties of AAT-008 were also assessed in rats (Sprague-Dawley, male), dogs (beagle, male), and monkeys (cynomolgus, male). The experimentally determined parameters are summarized in . A

• br Materials and methods br Results br Discussion In rodent

  2020-05-06

  

  Materials and methods Results Discussion In rodent species, CYP2E1 and CYP2B have been implicated in CCl4 metabolism. In this study, we used expressed human CYP2E1 to show that this enzyme is a high-affinity catalyst responsible for low-dose CCl4 metabolism. Studies employing an inhibitory

• br Introduction Plasmodium falciparum malaria

  2020-05-05

  

  Introduction Plasmodium falciparum malaria continues to be a major global cause of mortality and morbidity. Malaria treatment and control has been complicated by the emergence of resistance to widespread antimalarial drug use. The most common method for measuring antimalarial resistance is estima

• Possibly there are similarities among euphorb

  2020-05-05

  

  Possibly there are similarities among euphorb plant species but extraction of the HG-10-102-01 present in the microsomal fraction is needed for testing their preferences for substrates. Although R. communis, E. lathyris and E. lagascae belong to the same family, the DGAT activity of their microsoma

• Other mutations in the SYNE region exons have

  2020-05-05

  

  Other mutations in the SYNE1 3′ region (exons 81–85) have been implicated in an upper motor neuron disease, ARCA1 (Gros-Louis et al., 2007). The disease is characterized by progressive movement, coordination, and balance problems caused by disrupted Purkinje cell function and their impaired signalin

• br Materials and methods br Results

  2020-05-05

  

  Materials and methods Results Discussion In this study, we uncovered a female-specific haplotype-MDD vulnerability association, by which a two-marker haplotype TG of rs4633-rs4680 may link to enhanced MDD risk in females. Female haplotype TG carriers were estimated to have a 9.17-fold incre

• In frame exon skipping of COL A has been

  2020-05-05

  

  In frame exon 41 skipping of COL6A3 has been suspected to be responsible for isolated dystonia in several human kindreds without muscular defects [94]. In order to validate their hypothesis, the authors used zebrafish to selectively knock down several exons in col6a3 and found a negative impact on m

• Introduction Enzymes have higher selectivity specificity and

  2020-05-05

  

  Introduction Enzymes have higher selectivity, specificity and efficiency than chemical catalysts. Due to their properties and their green chemistry, biocatalysts are widely used in food, textile and pharmaceutical industry [1], [2]. A high efficient biocatalyst for industrial applications must be s

• The differences between ground and transition state

  2020-05-05

  

  The differences between ground and transition state properties are exemplified by a comparison of our human–yeast results with those of a structural study of possible differences in ubiquitin-Uba-1 binding in yeast (known structure) with human (simulated in [12]). Their discussion focuses on Ubiquit

• CXC chemokines are primarily expressed in immune organs and

  2020-05-05

  

  CXC chemokines are primarily expressed in immune organs and the central nervous system: the mouse thymus and spleen (Heesen et al., 1996), chicken bursa (Liang et al., 2001), primate (Macaca mulatta) Gallein mg (Federsppiel et al., 1993) and cattle locus coeruleus, cerebellum and pons (Rimland et al

• CRF and urocortin produce marked effects on

  2020-05-05

  

  CRF and urocortin 1 produce marked effects on the chk1 inhibitor when administered both i.v. or directly into the CNS (Parkes et al., 2001). Systemic i.v administration of CRF and urocortin 1 cause a marked and long-lasting reduction in mean arterial blood pressure in rats Briscoe et al., 2000, Law

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