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s7694 CXCL mediated cell migration is facilitated by
2019-09-23
CXCL16 mediated cell migration is facilitated by the interaction of soluble CXCL16 with CXCR6, expressed predominantly on the cell surface of CD4+ Th1 cells, cancer infiltrating lymphocytes and platelets (Borst et al., 2012, Kim et al., 2001, Liao et al., 1997, Wilbanks et al., 2001). CXCR6 is invol
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By live imaging of GUL GFP we
2019-09-23
By live imaging of GUL-1-GFP, we observed the kinetics of aggregate movement within the cell. One of the marked characteristics of GUL-1-GFP cytosolic (but not nuclear-associated) aggregate motion was a “comet-like” movement that was found to be dependent on the presence of properly polymerized micr
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From the results of previous experiments with the
2019-09-23
From the results of previous experiments with the purvalanol B affinity matrix, it is not clear whether the selective capture of parasite CK1 enzymes is a reflection of their high abundance or rather their affinity for the ligand compared with other kinases present in the lysates. Based on compariso
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Estrogen related receptors ERRs are orphan
2019-09-23
Estrogen-related receptors (ERRs) are orphan nuclear receptors and have three members including ERRα, ERRβ, and ERRγ (Yasumoto et al., 2007). Though they are termed as ERRs due to the sequence homology with estrogen receptors, they don’t need to bind estrogens to exert action. Generally, ERRs bind t
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br Materials and methods br Results
2019-09-23
Materials and methods Results Discussion COX-2-mediated production of PGE2 is involved in cell growth and metastasis of many cancers. Previous studies indicated that COX-2 was overexpressed in many cancer tissues and that PGE2 increased cancer cell growth, a process that could be suppressed
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Although DP technologies are convenient for users
2019-09-23
Although 3DP technologies are convenient for users to manufacture devices automatically, the printing materials are inevitably limited by the manufacturers of 3D printers. Strategies are increasingly being developed to functionalize the raw printing materials or their printed devices with other phys
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br O GlcNAc transferase OGT belongs to the
2019-09-23
O-GlcNAc transferase OGT belongs to the metal-independent GT-B superfamily of glycosyltransferases, which has been well-reviewed previously [14,15]. OGT is an essential gene encoded on the X-chromosome, and it has two main regions: a long N-terminal tetratricopeptide repeat (TPR) region and a C-t
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In general up to date no study has considered
2019-09-21
In general, up to date, no study has considered thermodynamic modeling to estimate the 5-Methoxy-UTP and of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different DESs over
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This letter reports an ab initio study on the
2019-09-21
This letter reports an ab initio study on the X peaks of PES by including the SO effect. The multiplet split energies are calculated with the SO-MCQDPT2 method [21], and the so-called pole strengths are evaluated to simulate the relative intensities. The results are compared with the experimental PE
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Unlike previous studies examining COMT genotyping in healthy
2019-09-21
Unlike previous studies examining COMT genotyping in healthy controls seeking to explain impulsive behaviors, this study sought to examine COMT genotypes in a large sample of individuals with varying levels of gambling behavior to determine whether COMT Firefly Luciferase mRNA pathway was associate
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Introduction We have recently identified that
2019-09-21
Introduction We have recently identified that caseinkinase 2 (CK2) inhibition protects white matter (WM) from ischemic injury. We focused our research on CK2 because upregulation of CK2 activity is associated with many diseases, including ischemic injury [1,[6], [7], [8]]. This review highlights an
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RHA is an agricultural by product obtained from the burning
2019-09-21
RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the BAY 61-3606 and generation processes [8], [9]. If RHA produced at less than 700 °C, it chemica
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br Conclusion br Experimental NMR spectra were
2019-09-21
Conclusion Experimental NMR spectra were recorded on a Jeol spectrometer at either 270 or 400 MHz for 1H spectra and either 68 or 100 MHz for 13C spectra. All chemical shifts are quoted in ppm relative to tetramethylsilane. In the assignment of signals the abbreviation DHN is used for 2,3-dihy
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Given its high frequency it is not surprising that
2019-09-21
Given its high frequency, it is not surprising that different strategies have been developed to restore the sensitivity of EGFR T790M-mutant alkaline phosphatase inhibitor to EGFR inhibition. To date, several different strategies have been evaluated in both preclinical and clinical models, but only
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Our study found a significant association between
2019-09-21
Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P Solithromycin and status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between EGFR m
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