• The electrophysiological mechanisms underlying high frequenc

  2019-06-18

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• Introduction Neuroblastoma NB which arises from

  2019-06-18

  

  Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these

• The ability of tumors to progress

  2019-06-18

  

  The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe

• The prevalence of drug induced type Brugada

  2019-06-18

  

  The prevalence of drug-induced type 1 Brugada pattern among patients with clinical AVNRT was found to be 27.1% by our group [17]. This high prevalence has important implications in terms of the epidemiology of BrS. The prevalence of paroxysmal supraventricular tachycardia (PSVT) (AVNRT and AVRT) in

• After being secreted into bile and entering the intestine of

  2019-06-18

  

  After being secreted into bile and entering the intestine, ∼95% of the bile acids are returned to the liver through the enterohepatic circulation via an active transport and Chrysin by a specific bile acid transporter, apical sodium-dependent bile acid transporter predominantly in the distal ileum.

• br Cholera remains a serious global

  2019-06-18

  

  Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease

• Education is part of the foundation for a

  2019-06-18

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• The efficiency of additional strategies for eliminating

  2019-06-17

  

  The efficiency of 2 additional strategies for eliminating the substrate for AF maintenance in addition to PVI has been described. Linear lesions are commonly made at the roof between the contralateral superior PVs (roof line), and at the isthmus between the mitral valve and the left inferior PV (mit

• Education and lifestyle changes for

  2019-06-17

  

  Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev

• The results of our initial cross sectional

  2019-06-17

  

  The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t

• br An understanding of the global health burden of sex

  2019-06-17

  

  An understanding of the global health burden of sex work, including sex trafficking and transactional sex, is urgently needed to direct resources to very large and vulnerable populations. Estimation of this burden will be a challenge, but similar efforts have been undertaken in other populations a

• O efeito mim tico das pr ticas

  2019-06-17

  

  O efeito mimético das práticas exercidas pela Igreja Universal teve impacto substancial no campo religioso, influenciando inclusive instituições fora do neopentecostalismo. Por exemplo, mediante este processo, a Igreja católica redobrou esforços para ampliar seu capital político. Neste caso, Emerson

• Se trata de un planeta ideado por hombres y que

  2019-06-17

  

  Se trata de un planeta ideado por hombres y que alcanza C34 manufacturer su vez vida propia: una vida cuya cifra no puede ya descubrirse, porque obedece a una serie de leyes peculiares que sólo pueden ahora los lectores de ese mundo intentar descubrir parcialmente. Es el rigor absoluto de un orden p

• Early recognition of ICD lead malfunction is

  2019-06-17

  

  Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation

• In DC from A group

  2019-06-17

  

  In DC from A group only few genes appeared to be significantly and highly modulated (10 out of 84). The HIV natural ligands CCL4 and CD4, the HIV induced transcription factor IRF1 as well as the apoptotic genes BAD and CASP8 resulted down-regulated compared to monocytes at all the considered time po

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