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br Discussion Our results confirm that germline variations i
2019-06-14
Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP
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El autor otra vez se sirve
2019-06-13
El autor, otra vez, se sirve de Chucho Hegel y su contradiscurso para poner de manifiesto los caminos posibles de la subjetividad “negra” frente TAK-875 las interpelaciones externas. Como contracara del Profesor, Chucho Hegel, que ha tenido el mismo inicio intelectual del protagonista, logró trascen
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In summary Welch and colleagues
2019-06-13
In summary, Welch and colleagues\' review is important. Not all systematic reviews on the same topic reach the same conclusion, but the convergence between the Campbell and Cochrane reviews here could hardly be stronger. The additional network and subgroup analyses in the Campbell review find no evi
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Although other risk markers such as high amplitude
2019-06-13
Although other risk markers such as high amplitude J waves in the inferior leads have been suggested, a better scheme for risk stratification is necessary. The presence of a type I BS ECG pattern indicates the necessity for ICD brompheniramine maleate in patients with syncope of unknown causes. Cur
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Bisphosphonates are the cornerstone of management in
2019-06-13
Bisphosphonates are the cornerstone of management in postmenopausal osteoporosis with randomised trial evidence of reductions in vertebral fractures for ibandronate [15] and both vertebral and non-vertebral fracture rates for alendronate [16], risedronate [17], and zoledronic UNC 0642 [18]. Ibandro
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gdc-0980 Cost effectiveness is another major concern for the
2019-06-13
Cost effectiveness is another major concern for the governments in countries with public health system. Van-den Hout WB et al. at Netherlands [7] did a cost utility analysis showing the cost of radiation treatment including re-treatment for bone metastases using SF versus MF were €2438 versus €3311
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Extensive vascularization of the skeletal tissue suggests
2019-06-13
Extensive vascularization of the skeletal tissue suggests the importance of blood vessels in regulating its physiological functions. Endothelium, the innermost cellular layer of blood vessels forms a central component of the bone marrow vascular microenvironment [7]. Recent evidence support that a p
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br Material and methods br Results br
2019-06-13
Material and methods Results Discussion Conclusion Financial support Conflicts of interest Introduction Metabolic syndrome comprises a cluster of conditions, including obesity, insulin resistance, hypertension, and abnormal cholesterol levels, which together increase cardiovascu
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br Conclusion br Financial support This research was
2019-06-13
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra
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G nesis y antecedentes Juan Mar
2019-06-13
Génesis y antecedentes Juan María Gutiérrez nace en Buenos Aires, meses previos cycloastragenol la Revolución de Mayo de 1810, donde las efemérides continentales marcan el inicio de la independencia del Río de la Plata y de casi todas las regiones dominadas por el imperio español. Es, por tanto, hi
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Pudo un Max Aub que
2019-06-13
¿Pudo un Max Aub que conocía de primera mano los ambientes de galería y de taller, incluyendo el de Picasso en París, se jactaba de un olfato para la pintura que le llevó fccp comprar a Ramón Gaya su primera acuarela cuando nadie lo conocía (Aub, 1971b: 403), y no viajaba sin su pequeño juego de mat
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energy metabolism It is well known that the precipitation of
2019-06-13
It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase
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However despite the strength of the research
2019-06-13
However, despite the strength of the research by Shawar and colleagues, any given process tracing case study can always be improved. In relation to this Article, the empirical tracing of causal processes could be strengthened further in future research, in particular by telling us more explicitly wh
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El n mero de correspondiente al primer semestre de
2019-06-13
El número 58 de correspondiente al primer semestre de 2014, ofrece la sección Movimientos sociales y democracia en América Latina, en la cual se encuentran temas de gran relevancia política y social para nuestra América. En primer lugar, el artículo “Sentidos de lugar y movimiento social: indígenas
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Desde otro contexto Andy Hargreaves
2019-06-13
Desde otro contexto, Andy Hargreaves planteaba en el año 2000 que las relaciones de la familia y la escuela también se tensionan en torno oxytocin receptor la estandarización: En el contexto internacional, tal como lo hemos ejemplificado del sistema escolar formal, Mathew Malkan plantea que los pro
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