• Elderly patients especially those in

  2019-05-08

  

  Elderly patients, especially those in excess of 70 years of age, are often quite fragile; such fragility may be secondary to aging or comorbidity. In this “susceptible” patient population, the negative influence of ET-adverse events on patient adherence to a medication regimen can be elevated. This

• The first variant in the non spine

  2019-05-08

  

  The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic melanocortin receptor lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to dete

• br Results br Discussion br

  2019-05-08

  

  Results Discussion Conclusions Disclosures Conflict of interest Financial support Introduction Stroke is one of the top five common causes of mortality in Malaysia with a rate at 8.43/100,000 Mifepristone [1,2]. Stroke impact is not limited to physical disabilities that stroke p

• br Conflict of interest br Acknowledgments br

  2019-05-08

  

  Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide olda Supplier pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome exp

• Causative genes for ARVC and

  2019-05-08

  

  Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table

• In silico prediction software SIFT PolyPhen

  2019-05-08

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• Si bien esta amerita un an lisis detallado me detendr

  2019-05-08

  

  Si bien esta amerita un análisis detallado, me detendré en algunas cuestiones que considero clave para entender el modo en cómo resuelve Vigil la integración del pasado colonial. En primer lugar, aparece ya una clara intención de situar order Metformin éste como los orígenes de lo que será la nación

• Hill and colleagues estimate that

  2019-05-08

  

  Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher

• When the analysis was matching with propensity score OS

  2019-05-08

  

  When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic

• Dinoprostone has been administered either vaginally or

  2019-05-08

  

  Dinoprostone has been administered either vaginally or intracervically, rather successfully and without serious side effects in normal pregnancies. The most important adverse reaction of dinoprostone is uterine hyperstimulation. The incidence of uterine hyperstimulation ranged from 5% to 16% in pati

• Conflicts of interest br Introduction Hepatocellular carcino

  2019-05-08

  

  Conflicts of interest Introduction Hepatocellular carcinoma (HCC) is one of the most common cancers and is the second leading cause of cancer death worldwide. In 2012, 782,500 new HCC cases and 745,500 deaths were caused by this persistent disease worldwide, with about 50% of the total number of

• The primary tool in the pharmacological management of

  2019-05-08

  

  The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress

• br Introduction Patients with advanced breast

  2019-05-08

  

  Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly

• Current ASCO recommendations suggest initiating bisphosphona

  2019-05-08

  

  Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri

• br Signal averaged electrocardiography SAECG SAECG is a

  2019-05-07

  

  Signal-averaged electrocardiography (SAECG) SAECG is a high-resolution electrocardiographic technique developed in the 1970s for detecting patients who are prone to SCD after MI. It is based on the theory that lethal ventricular arrhythmias leading to SCD often have a reentrant mechanism. Reentry

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