• We have shown that long

  2018-11-14

  

  We have shown that long-term WL/CR modulates adipocyte differentiation of ASCs in human sWAT by inducing both positive and negative regulators of the IGF-1 system at early stages of adipogenesis. Importantly, we identified DIRAS3 as novel negative regulator of adipogenesis, which slows down this pro

• harpagoside In principle the screening for any type of drug

  2018-11-14

  

  In principle, the screening for any type of drug resistance by searching for mutations in inhA, katG, and rpoB would allow to limit phenotypic DST to isolates with a harpagoside identified in inhA, katG, and rpoB. Limiting phenotypic DST to isolates with a mutation identified in inhA, katG, or rpoB

• We have previously reported the CM chip that enables

  2018-11-14

  

  We have previously reported the CM chip that enables precise estimation of rare cell counts in blood including spiked-in cultured cancer amyloid (Yatsushiro et al., 2010; Yamamura et al., 2012). Although the CM chip produced excellent results in a preclinical study, we considered that precise enume

• Progress toward the treatment of three major parasitic disea

  2018-11-14

  

  Progress toward the treatment of three major parasitic diseases (sleeping sickness, Chagas disease, and leishmaniasis) was recently demonstrated in an article published online last month in the journal (August 8, 2016). Collectively, these three diseases affect 20 million people per year, resulting

• Although some earlier studies reported significant differenc

  2018-11-14

  

  Although some earlier studies reported significant differences in RFS and PFS rates between risk groups (Xu et al., 2013; Altieri et al., 2012; Van Rhijn et al., 2010), other studies including ours (Fig. 1), found that prediction of both recurrence and progression were poorly discriminated by the EO

• br Methods CHC patients receiving anti

  2018-11-14

  

  Methods CHC patients receiving anti-viral therapy were consecutively recruited as a prospective follow-up cohort at one tertiary hospital and two core regional hospitals from 2002 to 2012. All the participants received peginterferon alpha-2a or peginterferon alpha-2b plus ribavirin. Patients were

• The outcome measures of efficacy of antibody replacement the

  2018-11-14

  

  The outcome measures of efficacy of antibody replacement therapy are summarized in Table 3 and Fig. 1. Anamnestically patients had a median number of 5.50 infections per year (interquartile range 4.00–8.00; available in 50 patients). In the year prior to ART the median number of antibiotic courses w

• In the publication by Sampath et

  2018-11-14

  

  In the publication by Sampath et al. () several lung transplant patients were identified with infections in association with pleuritic, surgical site infection and/or mediastinitis. These findings are unexpected to some degree, as historically has often been dismissed as normal genital flora (). How

• br Experimental design materials and methods Kinetic Fitting

  2018-11-14

  

  Experimental design, materials and methods Kinetic Fitting: we used a fitting procedure that minimizes the error between the experimental data (concentration of the final double stranded complex as a function of time) and the solution of the model as obtained with an ordinary differential equatio

• Bare frame structures as well as structures with

  2018-11-14

  

  Bare frame structures as well as structures with fully or partially unreinforced masonry infilled frames with or without openings have been analysed, in order to examine the influence of infill walls. A lot of parameters have been considered for each case. Infill panels are either 0.15 or 0.25m thic

• br Materials and methods br Results

  2018-11-13

  

  Materials and methods Results Discussion In the present study, we investigated neural response patterns of all four central subcomponents of reading, i.e. prelexical, orthographic, phonological, and lexico-semantic processing in a large sample of normally developing German-speaking children

• About mL of freshly prepared matrix guest solution

  2018-11-13

  

  About 2mL of freshly prepared matrix/guest solution was placed in the target holder inside the vacuum chamber and the target was frozen by placing it in thermal contact with liquid nitrogen contained in a reservoir connected to the MAPLE deposition system. The target temperature was lowered to about

• Temperature rhythm is an important phase marker for chronobi

  2018-11-13

  

  Temperature rhythm is an important phase marker for chronobiological studies, however, the use of core body temperature rhythm in longitudinal researches has always been limited by restrictions for continuous use of data recording devices, such as rectal probes. Wrist temperature, recorded by a ther

• The components present in the gas

  2018-11-13

  

  The components present in the gas detecting system are: Result and discussion The system developed was able to work with a power supply of 5V while most detectors need a minimum of 24V for proper functioning. The life of sensor is also stable and with proper calibration has a minimum lifetime of

• Introduction Microelectrode arrays MEAs are substrate integr

  2018-11-13

  

  Introduction Microelectrode arrays (MEAs) are substrate-integrated extracellular electrode matrices kept in contact with d-cycloserine in culture. MEA-based cell electronic interfaces enable the study of neuronal network processes, the evaluation of the effects of drugs and the electrophysiologica

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