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Ten strains of lactobacilli TMW isogenic with
2024-12-25
Ten strains of lactobacilli: TMW 1.1434 (isogenic with strain F19 ), TMW 1.1733 (isolated from fermented food), TMW 1.1628 (isolated from baby feces), TMW 1.1609 (isolated from baby feces), TMW 1.1734 (isolated from fermented food), TMW 1.313 (isolated from non-pasteurized Heineken beer), TMW
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Moreover showed reduction in fibroblast growth factor induce
2024-12-25
Moreover, showed 73% reduction in fibroblast growth factor–induced neovascularization in a mouse corneal micropocket assay at a dose of 100mg/kg and 50% reduction at 50mg/kg. Both results were highly statistically significant (PPU-WS13 have recently shown only moderate efficacy (40% inhibition) in
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At present the role of autophagy in neurons
2024-12-25
At present, the role of autophagy in neurons remains controversial. Autophagy has homeostatic and waste-recycling functions and plays a protective role in neurodegeneration diseases. Moreover, it has been thought as a programmed cell death participating in the occurrence and development of various d
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The downstream targets of ATR involved in
2024-12-24
The downstream targets of ATR involved in mediating human telomerase recruitment have not yet been identified. Under stalled fork conditions, activated ATR is able to phosphorylate and activate ATM (Stiff et al., 2006, and Figures 4C and 4D); whether this Melittin synthesis of ATM participates in a
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In the nineties we knew
2024-12-24
In the nineties we knew that (-)baclofen was the stereo-selective ligand for the GABAB receptor which had been recognised by Norman Bowery as a receptor for GABA, which was different from the GABAA receptor (Hill and Bowery, 1981). GABAB receptor antagonists were also synthesised and made available
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br Introduction Rhamdia quelen jundi Silurifomes Heptapterid
2024-12-24
Introduction Rhamdia quelen (jundiá, Silurifomes, Heptapteridae) is a neotropical catfish widely distributed in Central and South America (Silfvergrip, 1996). This species shows high potential for the aquaculture industry, due to an elevated growth rate, good carcass yield, and easy reproduction
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br The role of apelin in hypertension diseases The
2024-12-24
The role of apelin in hypertension diseases The role of apelin and its receptor APJ in cardiovascular diseases has been described in numerous studies (Table 2) [36,37]. It has been revealed that exogenous apelin may lower blood pressure. Tatemoto et al. [6] have discovered that different forms of
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According to the present observations the Ampk isoform
2024-12-24
According to the present observations, the Ampkα1 isoform promotes AP-1 transcriptional activity and thereby fosters er tracker green of AP-1 target genes in cardiomyocytes via activation of Pkcζ. The transcription factor AP-1 plays a decisive role during cardiac remodeling [24], [25], [26], [37]. A
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We provide here direct evidences that AT receptors
2024-12-24
We provide here direct evidences that AT1 receptors are active in ADSCs since Ang II induces intracellular Ca mobilization in these cells. Data obtained during the observation of Ca influxes led us to the search for the ADSCs subpopulation constantly expressing AT1 receptor. ADSCs are necessary for
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Numerous epidemiological studies document fewer cardiovascul
2024-12-24
Numerous epidemiological studies document fewer cardiovascular events and increased survival of non-CKD individuals treated with angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARBs) [8], [9]. By contrast, there are few studies of cardiovascular benefits of interruption
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br Materials and method br Result and discussion br Conclusi
2024-12-24
Materials and method Result and discussion Conclusion Acknowledgments This work is partly supported by the University Research Committee (URC) of the Senate of The Federal University of Technology, Akure. The authors thanked IFS for the funds (F/4449 1F and F/4449-2F) used to purchase th
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Previous studies to investigate the functions of AHR in Treg
2024-12-24
Previous studies to investigate the functions of AHR in Treg fruquintinib have employed a loss-of-function approach, using AHR complete-null mice, or a gain-of-function approach by ligand administration. However, these approaches may confound the interpretation of the results. For example, the broa
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Our previous study revealed expression of AhR in human
2024-12-24
Our previous study revealed expression of AhR in human parotid gland in cytoplasm of striated duct Traditional Chinese medicine (Drozdzik, Kowalczyk, Urasińska, & Kurzawski, 2013). In a further study we observed regulation of AhR expression and function by its specific inducer, i.e. 2,3,7,8-tetrachl
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As described in the introductory section the
2024-12-23
As described in the introductory section, the rotifer nervous system would be capable to transmit CGP 35348 in throughout its neural pathways. In addition, Clément and Amsellem (1989) and Kotikova et al. (2001) suggested acetylcholine to be important for the functioning of rotifer muscles and their
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Introduction Myasthenia gravis MG is an autoimmune disorder
2024-12-23
Introduction Myasthenia gravis (MG) is an autoimmune disorder characterized by muscle weakness, which is mainly due to autoantibodies reducing the number or function of postsynaptic p2y inhibitor receptors (AChRs) [1], [2]. Animal models have been developed to uncover the immunopathogenesis of MG.
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