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br Results with scrubbing process Based
2020-01-21
Results with scrubbing process Based on dofetilide discussion of Section 4.4 and area availability results of the previous section, scrubbing process, at the pixel processing rate, was included to mitigate error accumulation on the arrays and on the line-buffer. Eight sequential signals, plus the
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br Materials and methods br Results To
2020-01-21
Materials and methods Results To investigate the effect of 17βE on cell proliferation in the human renal tubular epithelia, BrdU uptake was measured in HRTEC primary and 3D-HRTEC cultures, allowing determination of the DNA replication rate. Representative microphotographs show BrdU uptake in H
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Progesterone s metabolite THP may also
2020-01-21
Progesterone\'s metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, Moxifloxacin sale and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans
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br Results br Discussion The nitric oxide cyclic guanosine m
2020-01-20
Results Discussion The nitric oxide-cyclic guanosine monophosphate pathway plays an important role in normal EF, and oral PDE-5Is were developed in the late 90s after the discovery that ED occurs when there is a problem with this pathway. Since then, several PDF-5Is with different pharmacokine
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br Results and discussion br Conclusions In conclusion we
2020-01-20
Results and discussion Conclusions In conclusion, we have developed rational strategies that allowed us to successfully identify a series of novel analogs structurally related to to modulate the activity of estrogen-related receptors (ERRγ and ERRβ), which are constitutively active. All of th
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While showing that deletion of EP maintains femur
2020-01-20
While showing that deletion of EP1 maintains femur bone volume fraction and trabecular bone parameters during aging, perhaps more importantly we have also demonstrated that increased initial BV/TV in EP1 is protective against OVX-induced bone loss. That is, while mice lose an approximately equal pe
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br Conclusion br Introduction Biological wastewater
2020-01-20
Conclusion Introduction Biological wastewater treatment is targeted towards the removal of phosphorous, nitrogen and organic substances by the metabolic activity of a diverse activated sludge microbial community. More precisely, it is based on the versatile catalytic activity of the microbial
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To provide a brief critical evaluation of this technology
2020-01-20
To provide a brief critical evaluation of this technology and an outlook, we note that performance of SMEPT is critically dependent on each of the components making up this platform, namely the substrate, the enzyme, and the prodrug. With regards to the latter, SMEPT is built on the experience and s
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br Conclusion In this study we
2020-01-20
Conclusion In this study, we investigated functional alterations of ECs following exposure to mechanical and/or physicochemical stimuli. Specifically, hypoxia induced phosphorylation with significant increases after 30 min and the maximum increase was after 180 min. Our data show that a combinati
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The total reduced glutathione content was determined in both
2020-01-20
The total reduced glutathione content was determined in both mln0128 to examine whether retinol was decreasing glutathione concentrations and thus decreasing the conjugation of NAPQI. Total hepatic (3.9±0.3 vs 4.9±1.0 μmol/g, retinol vs untreated, respectively) and renal (0.4±0.1 vs 0.2±0.1 μmol/g,
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The phenotypes of KD Ddr transgenic
2020-01-20
The phenotypes of KD-Ddr2 transgenic mice were less severe than expected from the results of miDdr2-transfected ATDC5 cells, which indicated that DDR2 might play important roles in endochondral ossification but neither critical nor essential roles in determining total body and skeleton size. The gr
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br Results br Discussion The sequence homology based cluster
2020-01-20
Results Discussion The sequence homology-based clustering of the human kinome by Manning et al. (2002) has been extremely useful to organize kinases into n methyl d aspartic acid by sequence relationship. Since kinases are such prominent drug targets, we expect that clustering of the kinases
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ARA metabolites which are produced through cytochrome P CYP
2020-01-20
ARA metabolites, which are produced through cytochrome P450 (CYP450) enzymes influence cardiovascular homeostasis. Human CYP4A11 and CYP1A2 metabolize ARA to 20-hydroxyecostearonic Paxilline (20-HETE) [11], which is a vasoconstrictor [12], platelet activator [13] and naturetic in the kidney [14]. O
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Compounds were prepared via the routes shown
2020-01-20
Compounds were prepared via the routes shown in , varying the sequence of reactions to install the thiazole or the phenyl ring at the end of the synthesis (pyridyl examples were prepared using similar chemistry). The aminothiazole building blocks were prepared as shown in . 5-Aminothiazole was prep
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We then explored the potential roles of vigilin along with
2020-01-20
We then explored the potential roles of vigilin, along with other proteins which have affinity for the 69 nt CSF-1R element, in breast cancer cells. The sequestration of these proteins by excess 69 nt pyrimidine-rich element increases CSF-1R levels (Figures 2 and 4), and as a result, increases the d
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